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No. Title Authors Journal
74 Rapid genome shrinkage in a self-fertile nematode reveals sperm competition proteins. Yin D1, Schwarz EM2, Thomas CG1,3, Felde RL1, Korf IF4, Cutter AD3, Schartner CM5, Ralston EJ5, Meyer BJ5, Haag ES6. Science. (2018) 359(6371): 55-61
Abstract
To reveal impacts of sexual mode on genome content, we compared chromosome-scale assemblies of the outcrossing nematode Caenorhabditis nigoni to its self-fertile sibling species, C. briggsaeC. nigoni's genome resembles that of outcrossing relatives but encodes 31\% more protein-coding genes than C. briggsaeC. nigoni genes lacking C. briggsae orthologs were disproportionately small and male-biased in expression. These include the male secreted short (mss) gene family, which encodes sperm surface glycoproteins conserved only in outcrossing species. Sperm from mss-null males of outcrossing C. remanei failed to compete with wild-type sperm, despite normal fertility in noncompetitive mating. Restoring mss to C. briggsae males was sufficient to enhance sperm competitiveness. Thus, sex has a pervasive influence on genome content that can be used to identify sperm competition factors.

/Presenter : Seongmin Cheon

/PMID : 29302007

/Date : 2018.03.23