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No. Title Date Creator
2 ‘Marine genomics’ 저널에 논문 게재 2016-05-28 17:41:24 csb_hhh (Manager)
조지훈 학생의 연구주제였던 돌기해삼(Apostichopus japonicus)의 세가지 종 청삼, 홍삼, 흑삼의 Transcriptome 분석 결과를 실은 논문이 2016년 3월에 국제학술지 ‘Marine genomics’에 최종 출판 승인 되었습니다.

6월 중에 온라인으로 출판 될 예정입니다.

공동 제1저자인 조지훈학생, 공동 저자인 천성민학생, 그리고 교수님 모두 수고하셨습니다. 축하드립니다!

논문명 : Comparative transcriptome analysis of three color variants of the sea cucumber Apostichopus japonicas

저자 : Jihoon Jo*, Jongsun Park*, Hyun-Gwan Lee, Elizabeth M.A. Kern, Seongmin Cheon, Soyeong Jin, Joong-Ki Park, Sung-Jin Cho, Chungoo Park

영문초록 : The sea cucumber Apostichopus japonicus Selenka 1867 represents an important resource in biomedical research,
traditional medicine, and the seafood industry. Much of the commercial value of A. japonicus is determined by
dorsal/ventral color variation (red, green, and black), yet the taxonomic relationships between these color variants
are not clearly understood.Weperformed the first comparative analysis of de novo assembled transcriptome
data from three color variants of A. japonicus. Using the Illumina platform, we sequenced nearly 177,596,774
clean reads representing a total of 18.2 Gbp of sea cucumber transcriptome. A comparison of over 0.3 million
transcript scaffolds against the Uniprot/Swiss-Prot database yielded 8513, 8602, and 8588 positive matches for
green, red, and black body color transcriptomes, respectively. Using the Panther gene classification system, we
assessed an extensive and diverse set of expressed genes in three color variants and found that (1) among the
three color variants of A. japonicus, genes associated with RNA binding protein, oxidoreductase, nucleic acid binding,
transferase, and KRAB box transcription factor were most commonly expressed; and (2) the main protein
functional classes are differently regulated in all three color variants (extracellular matrix protein and phosphatase
for green color, transporter and potassium channel for red color, and G-protein modulator and enzyme modulator
for black color). This work will assist in the discovery and annotation of novel genes that play significant
morphological and physiological roles in color variants of A. japonicus, and these sequence data will provide a
useful set of resources for the rapidly growing sea cucumber aquaculture industry.