조지훈 학생의 연구주제였던 돌기해삼(Apostichopus japonicus)의 세가지 종 청삼, 홍삼, 흑삼의 Transcriptome 분석 결과를 실은 논문이 2016년 3월에 국제학술지 ‘Marine genomics’에 최종 출판 승인 되었습니다.<br /> <br /> <br /> 6월 중에 온라인으로 출판 될 예정입니다.<br /> <br /> <br /> 공동 제1저자인 조지훈학생, 공동 저자인 천성민학생, 그리고 교수님 모두 수고하셨습니다. 축하드립니다!<br /> <br /> <br /> <br /> 논문명 : Comparative transcriptome analysis of three color variants of the sea cucumber Apostichopus japonicas<br /> <br /> <br /> <br /> 저자 : Jihoon Jo*, Jongsun Park*, Hyun-Gwan Lee, Elizabeth M.A. Kern, Seongmin Cheon, Soyeong Jin, Joong-Ki Park, Sung-Jin Cho, Chungoo Park<br /> <br /> <br /> <br /> <br /> 영문초록 : The sea cucumber Apostichopus japonicus Selenka 1867 represents an important resource in biomedical research,<br /> traditional medicine, and the seafood industry. Much of the commercial value of A. japonicus is determined by<br /> dorsal/ventral color variation (red, green, and black), yet the taxonomic relationships between these color variants<br /> are not clearly understood.Weperformed the first comparative analysis of de novo assembled transcriptome<br /> data from three color variants of A. japonicus. Using the Illumina platform, we sequenced nearly 177,596,774<br /> clean reads representing a total of 18.2 Gbp of sea cucumber transcriptome. A comparison of over 0.3 million<br /> transcript scaffolds against the Uniprot/Swiss-Prot database yielded 8513, 8602, and 8588 positive matches for<br /> green, red, and black body color transcriptomes, respectively. Using the Panther gene classification system, we<br /> assessed an extensive and diverse set of expressed genes in three color variants and found that (1) among the<br /> three color variants of A. japonicus, genes associated with RNA binding protein, oxidoreductase, nucleic acid binding,<br /> transferase, and KRAB box transcription factor were most commonly expressed; and (2) the main protein<br /> functional classes are differently regulated in all three color variants (extracellular matrix protein and phosphatase<br /> for green color, transporter and potassium channel for red color, and G-protein modulator and enzyme modulator<br /> for black color). This work will assist in the discovery and annotation of novel genes that play significant<br /> morphological and physiological roles in color variants of A. japonicus, and these sequence data will provide a<br /> useful set of resources for the rapidly growing sea cucumber aquaculture industry.<br /> <br /> <br /> <br /> <br />